Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

For medium risk CSPs, which of the following compounding processes qualifies?

1. Using a single dose for one patient

2. Multiple doses for a single patient on multiple occasions

3. Only non-sterile preparation

4. Using a sterile ingredient once

The correct answer is: Multiple doses for a single patient on multiple occasions

In the context of medium-risk Compounded Sterile Preparations (CSPs), the correct choice—multiple doses for a single patient on multiple occasions—aligns with the definition of medium-risk compounding established by the United States Pharmacopeia (USP). Medium-risk CSPs usually involve preparing multiple doses or a preparation that will be administered to one patient on multiple occasions. This can include batching of CSPs that may involve more complex procedures than low-risk compounding, such as the preparation of medications that require more than three components or those involving more than one sterile ingredient. This categorization recognizes the increased potential for contamination and the need for stricter adherence to aseptic techniques. The other options provided do not align with the criteria for medium-risk compounding. Using a single dose for one patient is characteristic of low-risk compounding. Only using non-sterile preparation falls outside the requirements for medium-risk, which must involve sterile components. Similarly, using a sterile ingredient only once does not inherently meet the criteria for medium-risk compounding, as it does not satisfy the provision of preparing multiple doses or ongoing treatment for a patient. Therefore, the scenario presented in the correct choice accurately reflects the framework for medium-risk CSPs as defined in pharmacy law