Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

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Single dose vials punctured in ISO Class 5 hoods must be used within how many hours?

3 hours
6 hours
12 hours
24 hours

The correct answer is: 6 hours

The correct answer is 6 hours because punctured single dose vials (SDVs) that are stored in an ISO Class 5 environment should be used within this timeframe to ensure the sterility and safety of the medication. ISO Class 5 environments provide a controlled atmosphere that minimizes microbial contamination, making it suitable for aseptic preparations. However, once a single dose vial is punctured, the integrity of its contents can begin to deteriorate due to exposure to the environment, as well as the possible entry of contaminants. Thus, the 6-hour limit is established to safeguard against potential risks associated with microbial growth and to ensure that the medications are safe for patient administration. This guideline is particularly vital in pharmacy practice, where the efficacy and safety of compounded medications are critical. Understanding the implications of this timeframe helps pharmacy professionals implement proper protocols for medication usage and contributes to overall patient safety in pharmacotherapy.