Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

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What is the primary use of LA and XR opioids?

Acute pain only
Chronic pain only
Both chronic and acute pain
Postoperative pain management

The correct answer is: Chronic pain only

The primary use of long-acting (LA) and extended-release (XR) opioids is for the management of chronic pain. These formulations are specifically designed to provide a steady release of medication over an extended period, allowing for sustained pain relief without the need for frequent dosing. This makes them well-suited for individuals who experience ongoing pain conditions that require continuous analgesic therapy. Chronic pain can arise from various conditions such as arthritis, neuropathic pain, or cancer, and managing such conditions often necessitates consistent control of pain levels. While acute pain might benefit from short-acting opioids, the prolonged effects of LA and XR formulations make them inappropriate for conditions that are expected to resolve in a short timeframe. Furthermore, postoperative pain is typically managed with shorter-acting medications that allow for more immediate and adjustable dosing in response to fluctuating pain levels. In summary, LA and XR opioids are primarily indicated for chronic pain management, as their formulation and pharmacokinetics favor long-term use rather than short-term, acute applications.