Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

What schedule does phenobarbital fall under?

1. C I

2. C II

3. C III

4. C IV

The correct answer is: C II

Phenobarbital is classified as a Schedule IV controlled substance. This classification is based on its potential for abuse relative to other substances and the accepted medical use for treatment. Schedule IV drugs are considered to have a lower potential for abuse compared to Schedule I, II, and III drugs, and they are commonly prescribed for conditions such as anxiety and seizure disorders due to their therapeutic efficacy. The drug’s status as a Schedule IV substance is supported by its medical utility and the fact that its abuse potential is recognized but is significantly less than that of higher schedules. Schedule I drugs have no accepted medical use and a high potential for abuse, while Schedule II drugs have a high potential for abuse with severe psychological or physical dependence. Schedule III substances have a moderate to low potential for physical and psychological dependence. Therefore, placing phenobarbital in Schedule IV reflects its lower risk profile while still remaining under regulatory control due to its potential for misuse.