Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

Which of the following does not fall under Schedule II or III classification?

1. Secobarbital

2. Codeine

3. Barbital

4. Amobarbital

The correct answer is: Barbital

The classification of controlled substances is determined based on their potential for abuse and their accepted medical uses. Secobarbital, codeine, and amobarbital are all substances that are classified under Schedule II or III, reflecting their medical utility but also their potential for dependency and abuse. Barbital does not fall under the Schedule II or III classification because it has been largely replaced by newer medications and is not classified as a controlled substance in many jurisdictions. While barbital does have some potential for abuse, it is often regarded as less critical in terms of regulation compared to the other options listed. As a result, it is not assigned to the same strict schedules as the other substances presented. This classification helps ensure that medications with a higher risk of abuse are more strictly controlled, while lesser-used or replaced medications like barbital may not warrant the same regulatory scrutiny.